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fermionsnotbosons

fermionsnotbosons@lemmy.ml
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You are saying that sucralose (or a metabolite thereof) could alkylate DNA - and theoretically proteins too - correct? Like what sulfur mustard gas does?

I did a quick search and couldn’t find any papers demonstrating a mechanism of action for that, although I skimmed a few that postulated that a dichlorinated hydrolysis product might be the true carcinogenic agent. Do you know of any studies that demonstrate that the alkylation can happen, either in vitro or (ideally) in vivo? Or maybe some better search terms to use, that could be my issue…

I am truly curious about this, I never knew the chemical structure of sucralose until I read your comment and subsequently looked it up.

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"Drivers have long raised the insufferable heat they can face when out for a day of deliveries, especially in the hotter parts of the country. The fleet of UPS trucks doesn’t have any air conditioning to keep the drivers safe and comfortable during their long hours on the job. During the summer months, package cars can reach upwards of 130 F. This has led to far too many UPS drivers suffering from heat stroke on the job, and some have even died due to the excessive heat. With worsening global warming, these issues will only become more severe. "

This is why we need unions and direct action more than ever, and can’t rely on government entities (ultimately beholden to capitalist interests) to protect our health and safety while we’re on the job. What the fuck good is OSHA if it is allowing heat illness and heat stroke deaths to happen without holding UPS accountable? They should have had their operations shut down until they outfit every truck with AC, and be fined into oblivion until they do so. Instead, OSHA does squat. Health & safety regulations are written in blood but OSHA’s bloody hands refuse to even touch the paper.

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The last half of Flamethrower does it for me, so damn cool when that synth comes in. They didn’t play that live at the show I went to, so the best song I’ve heard them play live is Gila!. The entire audience chanting Gila! while pumping their fists in the air was a pretty badass memorable concert experience.

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I love Lauren’s videos so much! His attention to detail, editing skills, and comprehensive story telling are second to none. I hope he keeps making videos through the entire run of the show; I know he took a break during the negativity surrounding the end of season 1 but his content always elevates the original works for me - and I mean both the books and the show!

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Love the trailer! I’ve probably seen it 10-15 times now between my own views and watching others react or live stream to it.

I am incredibly hyped to see Nynaeve’s episode dealing with those arches; it looks like she comes out of it with two wounds in her abdomen and I can’t wait to see how that goes down. Also, Perrin fighting Whitecloaks - it’s going to be badass to see the antagonism between he and they ratchet up a notch.

Other highlights/observations

No sign of Padan Fain (unless it was super subtle)

Turak v. Rand is going to be epic

Dude with flaming sword killing a fade, wtf is going on there (I need to know)!?!?

Egwene’s face @1:02 in the trailer, she’s wearing some unfortunate neckwear and looks in bad shape

Whitecloaks or Heroes riding through the dust/smoke @1:22???

Rand meeting Siuan (so glad we’re getting this scene!) - does Lan teach him Cat Crosses the Courtyard?

Aviendha looks deadly as hell in combat from the brief glimpses

Very excited to see what the great writers, actors, and other crew members have put together for us lucky fans. I hope they get what they’ve rightfully earned by their hard work, solidarity with WGA and SAG-AFTRA all day.

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Great non-canon line at the end from Siuan - “You are the water that turns the Wheel itself.”

I wish we got to see more of new Mat in the trailer but I guess I can wait. What we got were snippets of some epic moments: the darkfriend social, Rand meeting with Siuan, Nynaeve’s Accepted test, Rand v Turak, Heroes of the Horn (I think I see them on horseback @1:22 or so, may be a stretch, lol), and Aviendha (and Perrin!) in action v Whitecloaks.

I was already looking forward to the next season, especially sharing it with my show-only fan wife who loved season 1, and now we are both completely hyped for this second, atmospherically more ominous (I predict), season.

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Large consensus says he’s a specific person at the table at the Social.

Of course, how did I not think of that! Thanks, I was thinking about Bors and some of the other characters that might have been there, but totally forgot Fain. Time to zoom in on that shot to see some more details, lol.

My latest thought is: what scenes shown in the trailer are more TDR than TGH? That scene near the end with Mat driving his spear into something (or someone) is immediately followed by an explosion at what looks like a castle or fortress - if those shots are actually connected, then this is very reminiscent of his activities near the end of TDR. But other than that, most every scene I recognized looked to be from TGH (which is not necessarily a bad thing, since I think TGH has more television-friendly moments in it throughout than TDR does).

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Oh yeah, haha, that shot of Selene against his chest gave me chills! I look forward to seeing how they handle their time together on screen. It would be interesting if the show alters the relationship dynamic a bit to add some more reciprocation (from Rand) and overall nuance to it. In the books the dramatic potential felt very underutilized, and just kind of ‘haha, look at this naive farmboy not knowing how to handle a woman that knows what she wants’ - which to me just seems so cliche and uninteresting.

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Question: who is the little girl holding ‘the Dark One’s’ hand at the darkfriend social?

I have no idea and am wondering if anyone else does. Unraveling the Pattern points the girl out in his trailer breakdown on his youtube channel. It’s really hard to see in the original trailer without brightening the shot a bit.

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In addition to the great suggestions others have already provided, check out Emma Goldman’s writings if you haven’t already. They might appeal to you and she has some interesting takes.

Here’s a good starting point: http://dwardmac.pitzer.edu/Anarchist_Archives/goldman/GoldmanCW.html

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