In what sense? Aside from whether it’s practical to really desire nothing, if you could wouldn’t you be free by definition because you could do and have absolutely everything you wanted, that being nothing?
At the very least and no matter how humble your threshold is, everyone wants food, shelter and some kind of company.
The first 2 cannot be attained for free in our world’s ergo, you cannot be free from whatever obligations you may incurr to procure them
This is all nice theoretical advice… Not to be used literally in practice