You can try, but people won’t be as thrilled for TES or Fallout without Bethesda, for example.
FO5 is going to be a FO76 tier disaster. With the show there has to be a ton of pressure to crank something out the door. Microsoft’s folks are probably beating down Todd’s door. Bethesda has never really understood the series anyways.
If TES6 comes out, it’ll have 3 skills and ignore all established lore to turn an interesting and nuanced character into Bad Guy who wants to destroy the world for no reason. Admittedly normies really like this version of the series, so maybe it’ll still be wildly successful.