Inscryption and Outer Wilds have unforgettable twists that will never be the same on any future replays. Portal 2 has some of the funniest dialogue ever.

Mario 3, Mario World, and Breath of the Wild all were revolutionary games, but offer nothing that wouldn’t be just as cool on a second playthrough.

Further, the existence of Mario Maker and Tears of the Kingdom would make a blind playthrough of older games underwhelming, unless you were willing to erase your memory of all games since the release of the target game.