One that comes to mind for me: “Whatever doesn’t kill you makes you stronger” is not always true. Maybe even only half the time! Are there any phrases you tend to hear and shake your head at?
On the rare occasions that I’ve dragged out “it is what it is”, I’ve really wanted to say something like neither of us can change it, and instead of working towards a solution, all you’ve done is COMPLAIN for the last hour. Now SHUT UP, accept the situation, and make yourself useful!