That’s the kind of catharsis I experienced at the end of Disco Elysium, so it’s definitely possible. I’m just wary of a more cosmic scale perspective since that’s the kind of dread I have a harder time dealing with. If it leans more heavily into the futility of existence, ultimate meaninglessness of being, final end of all things (heat death of the universe type beat) then that’s not the type of concepts I cope well with. Hell, just typing that out is putting more emphasis on those thoughts than I’m typically comfortable with.
Outer Wilds is not at all nihilistic but it definitely deals with some of the topics you’ve mentioned, so it might not be a good experience for you.
I absolutely adore the game but it can definitely trigger people. I hope you manage to reach a better head space one day so you can play it!