form drag is proportional to:

• The denisty of the medium.
• The velocity of the moving body (squared).

Interstellar space might be very undense, peaking at about 10^-15 kg/m^3…

However the enterprise E is very fast, with warp 9.9 being approx 20,000 c or 6 * 10^13 m/s, and that matters twice as much

This puts the overall cosmodymanic forces at Cd * 3.6 * 10^12 N/m^2 or approximately the same as experienced by a Sandworm going mach 30.

So sure why not, Einstein and Newton are dead so can’t complain, and I’m pretty sure I could beat up Bill Nye.