The benefits is that every device is safer and with way less ads but some sites may break so I dont know
I use nextdns and adguard dns. Both have served me well.
I personally use Adguard home on my home network but I also have nextdns on my personal devices. I haven’t had issues with either of them. Both have pretty similar interfaces, Nextdns was easy to set up and I self host adguard home so it’s a tad more complicated. I have to say nextdns offers a lot more blocklists though, ended up only using a few of the blocklists I’m familiar with because I ended up blocking google and facebook stuff that broke some websites. But that’s more of my fault for not reading which blocklists I turned on than a nextdns problem. Though, it would help if they were to put warnings on potential blocklists that tend to break websites.
Also self-hosting AdGuard, I like it since I can add any sites to my whitelist/blacklists.
At home, on top of AdGuard, I still use Ublock Origin, Ghostery, NoScript, Decentraleyes, and Privacy Badger, a VPN and a privacy focused browser like Firefox or Vivaldi (even though all this much would actually makes a unique fingerprint of my browser…)
I will admit that NoScript is a pain having to manually approve JavaScript on websites before they will work properly, but its also eye opening.
For mobile, anything I’m not running through my home WiFi I use AdGuard’s public DNS in addition to a VPN.