In other words, is there any individual cell that can decide between two or more options, or all they all solely chemical and mechanical reactions without any self-determination at all?

18 points

“self-Determination” and “decision-making” are conscious, complex processes. A single cell is incapable of that.

On the other hand, how do we as humans form decisions? We use sensory input from various organs, process those by combining with existing knowledge/memories and form decisions based on that. But in the end, it’s still all based on “chemical and mechanical reactions”.

You quickly get into philosophical territory there: is our conscious self more than the sum of all the processes in our brain? Is there some extra “spark” that allows true self-determination, or are all our decisions a given result of the exact state of our brain and body?

permalink
report
reply
1 point

I think you’re projecting consciousness onto those terms more than you need to. An algorithm is a decision-making process devoid of consciousness (as far as we know). AI is capable of self-determination in as far as it’s capable of acting without reacting, or without total dependence on input. We just need our self-determination and decision-making to be special, so we present them as functions of our consciousness.

And a curse on any philosopher that tries to define consciousness as some variation of “that thing that makes human special”, any work they build on that is doomed.

permalink
report
parent
reply
1 point
*

I think that the illusion of free will is based on the fact that we’re conscious and thus have preferences and since decisions naturally tend to align with said preferences it then feels like we’re in control. However, nobody chose their likes and not-likes.

I think Brian Greene put it nicely; we don’t have free will but we have the experience of freedom

permalink
report
parent
reply

Immune cells form from stem cells. From start to finish in the stem cell differentiation process, four major changes occur. Some of these changes can have up to four potential outcomes each. Here’s a map:

While all cells react to their environment based on environmental stimuli and feedback loops, even bacteria and archaea, this is a great example of cell differentiation. All our cells started as stem cells, but the immune system’s continuous and consistent use of the process is very unique. It’s also the most elaborate and the image is surface level. Most the end cells pictured here will become more specific. Like there’s many different T-cells, even T-cells which change so much they don’t meet the classification of being a T-cell. The CD16 T-cell is a great example of this happening.

I feel like this is what you were looking for, but I’m not totally sure.

permalink
report
reply
4 points

Thanks! Is there a point during which any of these cells makes a decision that is not 100% mere chemical or mechanical reaction to their immediate environment? Perhaps when they need to differentiate into a new cell?

permalink
report
parent
reply

I mean, cellular/molecular biology is applied organic chemistry. It’s all chemical based in some way or another. I guess with T and B cell receptor formations, each receptor binding domain is made totally at random. So much so, they go through training to ensure they won’t attack self and are able to detect pathogen associated molecular patterns. Wildly, most T and B cells don’t pass training and get recycled, more or less.

So maybe, but you’re talking about the world on the cellular level, it’s all based on chemical reactions with environmental stimuli. To be alive requires responding to your environment, and chemistry is how that works at the microscopic level.

permalink
report
parent
reply
9 points

The function is in the interconnection and collaboration of the parts of the system. A screw or a round rubber also doesn’t drive you to work. It’s the whole car consisting of several parts that work together that does it. Also a single cell is a tiny part. There isn’t much in a single cell if we look at a complex process like making a decision.

permalink
report
reply
5 points

Just to spur this question on a bit, I know from my limited knowledge that cells can kill themselves when a mutation has occurred. But that’s also a sort of biochemical reaction. To be honest, what is truly self-determining? Is it simply a property of the nervous system? My thoughts are leading in that direction to be honest.

permalink
report
reply
3 points
*

There are good answers about differentiation from stem cells, process governed by the evolutionary determined genetic information stored within the cell itself. This genetic information was/is influenced by environment but that influence tends to be slow and subtle.

I have another answer to contribute. Metastatic cancer cells. These are cells which detach from primary tumors in any part of the body, then have to break into the lymph or blood and then they in a sense “decide” where they want to settle. We now know they’ll have preferences: some cancers will metastase to liver, some to lung, some to brain; but before they do so, these cells will literally circle around the body, searching for a “perfect spot”. Once they find it, they settle, often entirely changing their O.G. tumorous behaviour in the process which in return makes them super unpredictable and hard to kill. And all it takes is one wandering cell.

permalink
report
reply
1 point

Super interesting! Why do we think that they decide, and how do they make that decision??

permalink
report
parent
reply

Ask Science

!askscience@lemmy.world

Create post

Ask a science question, get a science answer.


Community Rules

Rule 1: Be respectful and inclusive.

Treat others with respect, and maintain a positive atmosphere.


Rule 2: No harassment, hate speech, bigotry, or trolling.

Avoid any form of harassment, hate speech, bigotry, or offensive behavior.


Rule 3: Engage in constructive discussions.

Contribute to meaningful and constructive discussions that enhance scientific understanding.


Rule 4: No AI-generated answers.

Strictly prohibit the use of AI-generated answers. Providing answers generated by AI systems is not allowed and may result in a ban.


Rule 5: Follow guidelines and moderators' instructions.

Adhere to community guidelines and comply with instructions given by moderators.


Rule 6: Use appropriate language and tone.

Communicate using suitable language and maintain a professional and respectful tone.


Rule 7: Report violations.

Report any violations of the community rules to the moderators for appropriate action.


Rule 8: Foster a continuous learning environment.

Encourage a continuous learning environment where members can share knowledge and engage in scientific discussions.


Rule 9: Source required for answers.

Provide credible sources for answers. Failure to include a source may result in the removal of the answer to ensure information reliability.


By adhering to these rules, we create a welcoming and informative environment where science-related questions receive accurate and credible answers. Thank you for your cooperation in making the Ask Science community a valuable resource for scientific knowledge.

We retain the discretion to modify the rules as we deem necessary.


Community stats

  • 563

    Monthly active users

  • 217

    Posts

  • 3K

    Comments