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The population of the entire world has been obliterated by a pandemic of vampire bacteria. Yet somehow, Robert Neville survived. He must now struggle to make sense of what happened and learn to protect himself against the vampires who hunt him nightly.

As months of scavenging and hiding turn to years marked by depression and alcoholism, Robert spends his days hunting his tormentors and researching the cause of their affliction. But the more he discovers about the vampires around him, the more he sees the unsettling truth of who is—and who is not—a monster.