Essentially, she was asking about the “long term side effects” of hrt. As someone with a weak grasp of my feelings and who has been wrong too many times in my perception of the future, I had to approach the question philosophically. I used the Marxist theory of knowledge as explained in Mao’s On Practice.

Experience is the ultimate source and test of knowledge. Experience generates rational knowledge and rational knowledge informs our perceptions and should be used when making decisions because empiricism gives one no agency. In learning about hrt I had the experience of fear and dislike of things associated with T, and a positive perception of certain “feminine” characteristics. After overthinking it I realize I am neutral on a lot of things and there is too much data to analyze regardless of my base pro and con list. But I also have the data points of other people’s experiences which are generally positive. Still I’m not the people I see online. I am unique and ever changing. I cannot know whether I want to transition medically until I have started.

Personal experience is the only thing that will be enough to be sure. Yes, I could eventually have tits and be infertile. So? I can detransition at any time in the worst case. There are many minor but notable changes E can cause way before the big stuff. Those will be valuable practice which will probably be a gold standard for the rational knowledge for knowing whether to go on with bigger changes.