Getting there:
In preclinical trials, participants received a dental lozenge the size of a cough drop, with a core of calcium and phosphate coated in a layer of peptide-infused flavoring.
Not yet:
Further research is needed to investigate the permeability and chemical stability of the mineral layer to achieve an effective, easy-to-apply treatment for dentin hypersensitivity, including implementing the peptide-guided approach under in vivo conditions.
Research article (Feb, 28, 2023): https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c01039