cross-posted from: https://lemmy.ml/post/14869314

“I want to live forever in AI”

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32 points

Even if you ignore all the neuromodulatory chemistry, much of the interesting processing happens at sub-threshold depolarizations, depending on millisecond-scale coincidence detection from synapses distributed through an enormous, and slow-conducting dendritic network. The simple electrical signal transmission model, where an input neuron causes reliable spiking in an output neuron, comes from skeletal muscle, which served as the model for synaptic transmission for decades, just because it was a lot easier to study than actual inter-neural synapses.

But even that doesn’t matter if we can’t map the inter-neuronal connections, and so far that’s only been done for the 300 neurons of the c elegans ganglia (i.e., not even a ‘real’ brain), after a decade of work. Nowhere close to mapping the neuroscientists’ favorite model, aplysia, which only has 20,000 neurons. Maybe statistics will wash out some of those details by the time you get to humans 10^11 neuron systems, but considering how badly current network models are for predicting even simple behaviors, I’m going to say more details matter than we will discover any time soon.

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15 points

Thanks fellow traveller for punching holes in computational stupidity. Everything you said is true but I also want to point out that the brain is an analog system so the information in a neuron is infinite relative to a digital system (cf: digitizing analog recordings). As I tell my students if you are looking for a binary event to start modeling, look to individual ions moving across the membrane.

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13 points

As I tell my students if you are looking for a binary event to start modeling, look to individual ions moving across the membrane.

So it’s not infinite and can be digitized. :)

But to be more serious, digitized analog recordings is a bad analogy because audio can be digitized and perfectly reproduced. Nyquist- Shannon theory means the output can be perfectly reproduced. It’s not approximate. It’s perfect.

https://en.m.wikipedia.org/wiki/Nyquist–Shannon_sampling_theorem

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2 points

It’s an analogy. There is actually an academic joke about the point you are making.

A mathematician and an engineer are sitting at a table drinking when a very beautiful woman walks in and sits down at the bar.

The mathematician sighs. “I’d like to talk to her, but first I have to cover half the distance between where we are and where she is, then half of the distance that remains, then half of that distance, and so on. The series is infinite. There’ll always be some finite distance between us.”

The engineer gets up and starts walking. “Ah, well, I figure I can get close enough for all practical purposes.”

The point of the analogy is not that one can’t get close enough so that the ear can’t detect a difference, it’s that in theory analog carries infinite information. It’s true that vinyl recordings are not perfect analog systems because of physical limitations in the cutting process. It’s also true for magnetic tape etc. But don’t mistake the metaphor for the idea.

Ionic movement across membranes, especially at the scale we are talking about, and the density of channels in the system is much closer to an ideal system. How much of that fidelity can you lose before it’s not your consciousness?

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2 points

Analog signals can only be “perfectly” reproduced up to a specific target frequency. Given the actual signal is composed of infinite frequencies, you needs twice infinite sampling frequency to completely reproduce it.

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2 points

Yes the connectome is kind of critical. But other than that, sub threshold oscillations can and are being modeled. It also does not really matter that we are digitizing here. Fluid dynamics are continuous and we can still study, model and predict it using finite lattices.

There are some things that are missing, but very clearly we won’t need to model individual ions and there is lots of other complexity that will not affect the outcome.

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