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In 2020, the EU reported 5800 drug overdose deaths in a population of 440 million. The same year, the United States, with a population of 330 million, reported 68 000 drug overdose deaths.(www.nytimes.com)

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ZodiacSF1969@sh.itjust.works
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Except for morphine, pretty much every opioid is just a chemical out body metabolizes into morphine

Only codeine and heroin have this as their primary mechanism of action I’m fairly sure? Oxycodone is active itself without metabolism, as are many other opioids.

Yes, metabolism will still make a difference though.

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