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4 points

@Gaywallet This particular link wasn’t opening for me. But what I have heard elsewhere is that there are indeed known to be a number of parts of the X chromosome which affect the immune system, in ways we are still in the process of figuring out.

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2 points

It’s an interesting article, and well exposed.

It basically goes to say that the inactivation mechanism (Xist noncoding RNA strand) which gets triggered when there are two X chromosomes present in a cell, almost completely coats one of the X chromosomes, disabling it… but the result is not completely inert, still allowing the attachment of other partial strands, in weird combinations that can lead to an (auto)immune response.

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