The game has a minor character who is trans too. It uses the world she invented but does not borrow her real world views
Just because a minority is depicted in a work of art does not mean that depiction was made in good faith. Americans are familiar with that concept because of our dark history of minstrel shows and blackface performances.
When the trans woman character’s name is Sirona Ryan, it calls into question whether she is meant to be a character or a caricature.