-21 points
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Ibuprofen does not reduce a fever, it reduces inflammation. Tylenol would have made this meme work

Edit: I was wrong

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83 points
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The first sentence on ibuprofens wikipedia page under “Medical uses”:

Ibuprofen is used primarily to treat fever

Anti-inflammatories reduce fevers, are there even anti-inflammatories that don’t have that effect to some extent?

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24 points

So I was about to correct you that Tylenol is actually acetaminophen; turns out paracetamol is just another name for the same chemical. TIL

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4 points

Huh. I didn’t know that either.

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21 points

they both come from the chemical name - para-acetylamino-phenol (or, more proper, N-acetyl-para-aminophenol). random people chose different parts to shorten the name

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5 points

I’ll be damned, I was almost certain it wasn’t an antipyretic, but it looks like I was wrong. Thanks for correcting me.

You didn’t need to use such condescending language though, there was no need to be rude.

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12 points

Apologies. I do think making it sting a little when correcting someone on something they should have double checked, is warranted, if for no other reason than to make it clear to others reading which take to go home with.

But in response to your edit I’ve softened my correction as well.

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-4 points

When you post wrong information online you’re responsible for perpetuating idiocy. Someone who had better things to do had to go out of their way, waste their time, to correct you.

Think before you post.

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14 points

Paracetamol is not anti-inflammatory in any serious context, which is to say taking paracetamol to reduce actual inflammation (think gout or rheumatoid arthritis) is more or less useless. From the wikipedia article on paracetamol:

Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This occurs only when the concentration of arachidonic acid and peroxides is low. Under these conditions, COX-2 is the predominant form of cyclooxygenase, which explains the apparent COX-2 selectivity of paracetamol. Under the conditions of inflammation, the concentration of peroxides is high, which counteracts the reducing effect of paracetamol. Accordingly, the anti-inflammatory action of paracetamol is slight.

It is, however, an analgesic.

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3 points

Man what is pain relief anyway

like it doesn’t seem to work after I wake up

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5 points
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Deleted by creator
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1 point

Nevermind that Tylenol’s effective ingredient is paracetamol, which is also “just” an anti-inflammatory.

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3 points
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Deleted by creator
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1 point

Paracetamol is not considered an anti-inflammatory.

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4 points

Take both at the same time. They’re synergistic and will reduce pain, inflammation, and fever better than a higher dose of each by themselves

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-8 points
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Deleted by creator
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-5 points

Tylenol is a brand of acetaminophen, which is bad for your liver.

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14 points

It’s metabolized by your liver, so is fat. It has a safe and therapeutic dosage range.

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16 points

I am bad for my liver.

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1 point
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-1 points
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Ibuprofen (or NSAIDs in general) is bad for the liver as well and worse for the kidneys.

Edit: confused kidneys and liver.

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1 point

Can’t ibuprofen also damage your liver?

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5 points

My understanding is that ibuprofen is processed in the kidneys, and if Tylenol was up for FDA approval today it would go down in flames due to safety concerns

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1 point
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Aspirin is bad for your liver as well, especially for kids. It disrupts the electron transport chain in the Krebs cycle which leads to fatty acids not being converted and since they don’t belong into the mitochondria, they are expunged into small deposits in the liver. It’s called microvesicular steatosis, or more commonly called fat liver.

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1 point

Big yikes

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127 points

Macrophages just want to watch the whole body burn.

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35 points

From what I’ve read, anything over about 101F is doing more harm than good.

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46 points

That’s 38C for anyone out of the US

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31 points

311 Kelvin for anyone who is an absolutist

And

560 Rankine for absolutists who wish to stick with Fahrenheit

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5 points

38C is a nice handful, not a temperature.

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8 points

That’s not very high

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9 points

Pretty sure it’s anything at 42°C or above that is a vital emergency, as it starts to destroy neurons

39°C is basically a normal fever

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22 points

This does not appear to match the evidence anymore: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717216/

The body is generally unable to raise the core temperature to the point where it can cause permanent damage, unless the ambient temperature is high. That is, unless there is a pre-existing heart or other vital organ condition.

In fact, fevers >=39C (102.2F) showed better outcomes in covid patients.

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3 points

I thought danger was at 104F??

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47 points

I only know ibuprofen as a pain killer, but good to know it can also reduce fever!

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21 points
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It was the key drug being deployed during the covid war. I survived tks to it. Saw god a few times.

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6 points

Reading this makes me think it was thorazine instead of ibuprofen.

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5 points

DMT is more likely.

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2 points

Interesting, as someone who takes Suboxone, I avoid Tylenol because of potential liver issues. I was told during the pandemic that ibuprofen caused things to be worse. It was a confusing time and a very scary time.

It’s hard to know what info to trust these days.

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55 points

It blocks inflammation of all sorts

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1 point
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61 points

To me Macrophages are the single most interesting creatures(symbiotes?) in the human body. I’ve read so much about them yet know so little.

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37 points

Its their body, we are just the pilot.

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11 points

Haha, yeah, sounds about right! No neurons, yet so determined.

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24 points

Watch cells at work, you will thank me later

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39 points

I’ve had this Excel workbook open for an hour now and my boss is asking why I’m just staring at it. But thank you?

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1 point

This sort of confusion just sheets me.

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11 points

Having a fever I can deal with, but I will immediately take some meds to not have a headache. Unfortunately, usually a fever comes with a headache.:(

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