Research identifies protein responsible for increasing inflammation and oxidative stress

A new study has identified a protein that nicotine-free vape fluid increases in the lung, causing damage including oxidative stress, inflammation and breakdown of the blood vessels.

The research, published in the journal Microvascular Research demonstrates a range of damaging pathways when an in vitro model of the human lung was exposed to a common brand of nicotine-free e-cigarette.

E-cigarettes have become increasingly popular in recent years and are often seen as harmless alternatives to cigarette smoking. It is estimated that there are almost five million ‘vapers’ in the UK, compared to around 700,000 in 2012.

3 points
Deleted by creator
permalink
report
reply
11 points

Hot oil? Since when does e-liquid contain oil?

permalink
report
parent
reply
1 point
Deleted by creator
permalink
report
parent
reply
11 points

And since when is propylene glycol an oil?

permalink
report
parent
reply
-6 points

E-liquid is often referred to as vape oil, both for nicotine and THC vapes.

permalink
report
parent
reply
5 points

I’ve been vaping for 7 years and I’ve literally never heard a single person IRL or on the internet call it “vape oil”. It’s vape juice.

permalink
report
parent
reply
3 points

the nicotine found in most vapes now days are the newer synthetic variety

after talking to the lab responsible we were told the main difference between synthetic and real is that the synthetic does not cause cancer

another difference is the real nicotine derived from the tobacco plant is usually sourced from India just like your kitchen spices like vanilla and is prone to contamination from ground pollution like heavy metals

synthetic nicotine solves several problems including reducing the strain on the planet by using less resources than required for growing large crops of tobacco

combine that with green chemistry which uses no heavy metals for a catalyst and you have a clean product

now onto flavorings

some such as isoamyl acetate for banana flavor are not very harmful to vape and is even used to test breathing equipment

extensive studies some on a global scale have been done to show the varying degrees of toxicity to nontoxicity on the various flavors

some flavorings are also good on the environment not only because of green chemistry but also with the newer technologies of reclaiming atoms and molecules from food waste

there is lab on the east coast of the US doing just that and making chemicals some for flavoring such as isoamyl acetate which has multiple applications

articles like this are deadest on turning back the clock on good science and good health

permalink
report
reply
24 points

Yea anything other that clean air like you find deep in the forests and prairies is bad for your lungs. Hardly news. Anything is better than American cigarettes though

permalink
report
reply
5 points

Just the American ones though, right? 🤣

permalink
report
parent
reply
7 points

Many nation’s cigarettes are just tobacco in paper, not nearly as bad as American companies putting literal rat poison and formaldehyde in the mixture

permalink
report
parent
reply
26 points

I really wish these articles would be more clear about what kind of vaping they are talking about. Vaping weed, for example, likely has a different chemical composition but might pose similar or very different risks that the article never acknowledges.

permalink
report
reply
5 points

I’ve seen previous studies about the flavoring used, as well. Something about how it’s a food flavoring only approved for eating, not for inhaling.

I don’t think I’ve ever heard of nicotine itself being a major contributor.

permalink
report
parent
reply
11 points

Weed vapes are typically just extracts from the cannabis plant, so their chemical composition should be completely different from the liquids used in nicotine vapes.

permalink
report
parent
reply
3 points
*

As another commentor mentioned, it would be great for these studies to include the relative harm to for example smoking cigarettes or as you mentioned vaping cannabis. Yes it is common sense anything but air in the lungs is bad, but how harmful?

permalink
report
parent
reply
3 points

Three vapes, all watermelon flavour, were purchased from an online retailer and contained different concentrations of nicotine: 0mg, 10mg and 20mg in a 2ml solution

permalink
report
parent
reply
3 points
*

Where the fuck can I buy 2ml of 20mg liquid? Standard these days since the dawn of mods is 3mg or 6mg, back around 2012ish you could get 3mg, 6mg, 12mg, 18mg, or 24mg, 10 or 20mg has never been a standard. On top of that the smallest bottle I’ve seen sold is 5ml testers, who the fuck sells 2ml?!

Even salt nic, it’s usually 25-50mg. 20mg salt nic would make sense but where the dick do I buy a 2ml bottle? That’s barely a bottle at that point it’s a damn vial, nobody sells that shit. Salt nic bottles are usuall all 30ml, never seen a 5ml, 60ml, or 120ml.

I’m gonna need this study to link me to the online retailer, because frankly I’m not sure I believe them.

permalink
report
parent
reply
4 points
*

Probably a European pod they’re often around 2ml. Maximum nicotine concentration here is 20mg/ml independent of buying a nicotine shot for mixing liquid yourself, or buying a ready to use flavoured one. Yuul responded to this limit by increasing it’s wick size and effectively increasing nicotine levels per hit above the American levels (of course using up pods much faster is a welcome side effect).

Edit: just look at the top sellers here for example https://www.dampfalarm.de/E-Zigaretten/Pod-Systeme/?p=1

permalink
report
parent
reply
1 point

I’ve been to shops that’ll keep keep nicotine concentrate around mix into the liquid if you want. They can also mix the 0mg variant in to reduce nicotine concentration. It’s possible something like that happened.

permalink
report
parent
reply
1 point
*

Those are standard strengths for freebase nicotine. Nicotine salt comes in different strengths. 50mg/ml and 35mg/ml are standard where I live in the US. Elfbars usually come in 40mg/ml.

permalink
report
parent
reply
47 points

Yeah bruh, breathing shit that isn’t air is probably not the best idea, generally speaking.

permalink
report
reply
25 points

Who would’ve thought… I wonder how vapes compare to living next to a main road, and if the government will ban ICE cars and air pollution if they’re just as damaging to our lungs?

permalink
report
parent
reply
6 points

Yes. Please ban ICE cars.

permalink
report
parent
reply

science

!science@lemmy.world

Create post

A community to post scientific articles, news, and civil discussion.

rule #1: be kind

<— rules currently under construction, see current pinned post.

2024-11-11

Community stats

  • 3.9K

    Monthly active users

  • 1.4K

    Posts

  • 15K

    Comments