Hard to say - There’s still a lot of hazards yet to be accounted for: a lot more radiation exposure, literal poison in the soil, severe weather, safe and affordable supply chain, etc.

I guess that depends on what you consider reasonable. I figure if they’re starting with simulations such as this now, it’s reasonable to expect an actual manned mission in maybe 20 years.

Antarctica trips have all of those limits you mentioned, they’ll just be worse for Mars. While they can operate sort of freely for a few months, once winter sets in, they are just as isolated as another planet. They just get the advantage of easier setup then Mars.

I’m thinking a lot of the equipment is different as well, and since they mention simulating equipment malfunctions, that plays an important part, especially with the additional limitations/simulated dangers.

those doing a antartic winter may as well have the no suited outdoor time, poor clothing choice will be death almost as quick