279 points

my dad is refusing to take vaccines because he thinks taking it will automatically make him vote dem because of nano-machine in them.

he also thinks vaccines are kind of HRT.

anyways how’s your day?

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169 points

sorry for your loss

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31 points

| ||

|| |_

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3 points

What is this??

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81 points
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I hope you are an adult and no longer live with your parents.

If that is the case remember this. If you cannot have pleasant encounters with him, you are under no obligation to have them at all.

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-2 points
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No obligation to keep seeing them, would be kind of hard not to have parents 😛

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24 points

You still have them, you just don’t have contact with them.

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1 point
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The “them” in that sentence refers to “encounters” not “parents”.

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48 points

Ah so that explains my D cups

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39 points

It’s all that government big pharma stuff that have given me moobs, things like:

  • Covid-19 vaccines;
  • Fluoride in toothpaste and tapwater;
  • Chemtrails;
  • a horrendous diet and little exercise;
  • pride flags
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34 points

pride flags

You weren’t supposed to eat them smh

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2 points

RIP your inbox.

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2 points
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I’ll show my man boobs to anyone who wants to see them. Usually people tell me to stop showing them and say things like “gross” and call me bear tits but that hasn’t stopped me from whipping them out on every occasion and non occasion

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27 points

Block his router of the content

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18 points

I watched birds are not real Ted talk the other day, I think it was awesome to give a perspective on the conspiracy stuff and how people run with it.

If it flies, it spies. 🐣

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17 points

Sorry you are going through that. Same thing happened to me, it really sucks :(

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28 points

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4 points

you should introduce him to the library

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4 points

Gives a whole new meaning to the term “parental controls.”

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2 points

If you have some disposable cash and you’re running into the “watch this video about antivax stuff”. I recently discovered Kagi’s summarizer works on as many YouTube videos as you want (seemingly by processing the audio itself).

It’s been a bit since I’ve received a video like that, but I think it’ll be a huge time saver for the next one… Or the next similar one…

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2 points

Is your father a senator?

Nano machines son

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149 points
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While I’m sure there is a crazy markup, it’s important to note the cost to produce - as in manufacture - does not include the cost of drug discovery, which is extremely expensive and involves a good amount of risk over a long period of time.

You can’t just compare the cost of discovering a new drug vs. cost of producing a generic without any research like that.

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138 points

https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

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45 points

Pfizer COVID vaccine wasn’t researched or developed by them. It was developed by the German BioNTech.

Still, bringing it to market at the required volumes requires extreme amounts of capital, there’s a reason no one can enter the club.

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14 points

I like Lemmy for exactly this - whenever someone incorrect makes a statement they’re factchecked.

Thank you kind person for finding and sharing that source.

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42 points

OP didn’t make an incorrect statement though. What they stated was an important part of the equation. I think a lot of people don’t take that type of thing into account and they will read what this post says and assume that Pfizer should be charging $13, or maybe something pretty close like 15 or 20. Clearly 1400 is far far too high, 13 is too low. A reasonable price allows the manufacturer to be successful while not gouging consumers lies somewhere in between, but much much closer to the low end than the high. To me that’s really what the person you are responding to is giving evidence for.

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4 points

Most excellent fact checking 👍

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50 points

R&D on drugs is insanely expensive, but the protections put in place with the pricing are also a bit absurd. Most drug companies will lock down the formula for a period of time and price the drug aggressively for a short time (like a few years) and then open the formula up to generics who buy it and sell the same damn thing for a fraction of the cost.

For clarity I’m agreeing with you that the price is largely due to non-manufacturing costs and the article is misleading as a result, but I also wanted to say that the whole industry is a testament to capital over humanity.

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27 points
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Fuck off with the big pharma apologetics.

Boo hoo the corporation got millions in taxpayer money to develop a vaccine and now they have to profit off of it. I feel so bad for them.

This is subtle astroturfing.

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34 points

By that same logic: it costs a couple of cents to burn a dvd or to transfer a few gigabytes, yet games costs $60.

All the commenter above you is saying is don’t mix up the cost to develop with the cost to mass produce,

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6 points

I’m going to be unreasonable because I don’t like the ethics behind Pharma companies.

They should eat the loss; their research was healthily subsidised by the taxpayer

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…and the video game industry makes more money than any other entertainment industry. Yes, these things should cost more than just their production cost, but there is currently an obscene amount of money being made by the people at the top of these industries - y’know, the ones whose main role in making and distributing the product is just already being obscenely wealthy. And while I don’t really care if AAA games are overpriced if they’re only $60, I do care if life-saving meds are being held for ransom.

Do y’all need reminded that insulin, a life-or-death drug that’s been around since the fucking 1920s, only costs at most $10 to make but currently retails for up to $300 a vial? It does not fucking matter whether or not this particular treatment should cost $13 or $90, the markup on any life saving drug being over 1,000% is blatant price gauging at the expense of human life, and the fact that the pharmaceutical industry does this all the time is common fucking knowledge. Anything approaching a defense of this shit either is in fact astroturfing or is so braindead as to call it a necessity that a publicly traded company demand the sick either choose debt or the grave.

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3 points

All the commenter above you is saying is don’t mix up the cost to develop with the cost to mass produce,

That cost to develop was likely not borne by Pfizer in the first place.

https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

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-2 points

Game DVDs are not lifesaving drugs.

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9 points

Are we talking about the vaccine here? Sounds like a post-exposure drug to me

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9 points

Guess this comment of mine will also get deleted but here goes nothing.

The article is about antiviral medicine, not a vaccine. So you are getting angry at the wrong thing.

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17 points

That’s just an excuse because many drugs are sold at prices much lower what they are sold in the US. They are not selling them at loss in other countries.

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0 points

Definitely not at a loss to produce no, but maybe a loss overall.

My bet is that the US subsidizes R&D by paying obscene amounts for the drugs and the EU and others just serve as extra income

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1 point
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Your bet?

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-2 points
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Deleted by creator
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0 points

That’s what they make you believe. Why American still pay high prices for insulin? It doesn’t cost that much to produce. It just those companies are paying politicians to keep things in their advantages and give you those excuses.

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13 points
Deleted by creator
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9 points
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Well here you go again when people with no scientific education pull up literature as a gotcha. Thanks for giving me flashbacks to the high times of the pandemic. Sorry for the harsh reply but its posts like this that just funnel into misinformation around this already heavily polarized topic.

To explain, Paxlovid is not a vaccine, it is an actual medicine/treatment. So it was not funded by taxpayers as the article states. Unless there is some other info on how this specific medicine was also funded by taxpayers of course, I am not an expert on research funding. But the article only mentions vaccine research.

That said, I also do not think its a fair price necessarily. But it is true one should not equate production price as a fair price as R&D of drugs have high costs, mostly also because a lot of drug programs fail, making all prior investment to them a loss.

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8 points
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Paxlovid is not a COVID vaccine, it’s an antiviral.

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2 points

Smh just use windows defender people

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4 points

I don’t think it takes 1.4k to move anything anywhere.

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-2 points

Yes we can. It’s just doesn’t give a good faith assessment of the situation. And why would I want to do that if it’s counter to my rigid world view? sigh better add an /s

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-7 points

It costs $13 to produce paxlovid…

Experts at Harvard University have estimated that the cost of producing a five-day course of nirmatrelvir-ritonavir is $13.

https://www.commondreams.org/newswire/pfizer-spikes-paxlovid-prices-to-100-times-cost-of-production

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139 points
Deleted by creator
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31 points
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5 points

Torches would burn the bodies too much. You need a proper grill.

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3 points

changes need to happen badly

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1 point

Sounds good. In the meantime, I’m going to buy some Pfizer stock for my kids sake.

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2 points

This comment is loaded with wishful thinking.

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2 points

That’s optimistic tbh. More like my comment is the result of 2 decades of fighting the good fight only to watch those I’m trying to help dig a deeper hole. Time to tend my little patch of grass, build a sturdy fence, and hope for a renaissance.

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106 points
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Intellectual property is a scam. A commonly heard defense of intellectual property is that it is needed for companies to fund their R&D. However pharmaceutical companies typically spent a lot more money on marketing & sales than they do on R&D. Big Pharma spending money on marketing and sales is harmful to our health. Apparently it’s a lot more lucrative to get people drugged up on painkillers or whatever than to discover new medicine. If we didn’t have intellectual property then we would have competition resulting in the lowest possible medicine prices. Companies would have no money for marketing so medicine would be judged on their actual properties, only the best would be given to patients, not the best marketed, but best health-wise. Companies would have no money for R&D either, but the government could fund R&D We shouldn’t blame the players, we created a system that produces these bad actors. Let’s change the system so that these bad actors couldn’t exist. Intellectual property is a international problem, join the pirate party of your country and let’s make it happen!

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84 points
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Deleted by creator
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33 points

There is some level of R&D they do to productize it, manufacturability and scaling. And running drug safety trials cannot be cheap, especially the liability insurance.

That all said, I think it’s criminal that the university labs pay so little. PhD students barely make over $40k, set by the NIH. Not adjusted for CoL either.

I think I have more of an issue with the for-profit nature of pharma companies. Shareholders shouldn’t be involved in medicine.

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28 points

I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations

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15 points
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The woman who got the nobel prize for the mRNA research that led to the Pfizer vaccine did a lot of it while employed at Pennsylvania University before they fired her because they didn’t see the research leading to making them money. Then she moved on to Biontech where she continued the research.

I’m not sure how much was done at the university but it was probably not insignificant and then biontech got lucky and snapped it up for basically free.

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3 points
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Deleted by creator
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9 points

I’m always curious about the actual numbers. Here’s their R&D budget by year:

https://www.statista.com/statistics/267810/expenditure-on-research-and-development-at-pfizer-since-2006/

And their overall revenue:

https://www.pfizer.com/sites/default/files/investors/financial_reports/annual_reports/2022/performance/

In 2020, their revenue was about $40B on $8.5B in R&D cost. They had a huge revenue increase the last few years, with 2022 being $100B, but R&D only increased to about $11B.

So they do have R&D, but it’s not that big compared to the money they’re bringing in. Their net income has increased substantially, as well.

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2 points

Thank you for finding the numbers

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1 point

In addition to that, I’ve heard that a large portion of that R&D spending is on iterating drugs they already own so that when the patent runs out they can patent a new version and lobby the old one to be made obsolete so generics can’t be made.

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1 point

Who wants unpaid internships!

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7 points
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AFAIK some US agency did R&D for COVID, they just bribed sponsored Right People

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101 points

The eu:

€20 take it or leave it

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39 points

Scandinavian countries:

Free, take it or leave it

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66 points

I don’t think he meant to the consumer. EU countries can negotiate for the price with pharmaceutical companies, so they can lower the price.

In the US insurance companies can try to negotiate, but their weight is quite low, and the federal government (medicaid, medicare) is forbidden by law to negotiate. Whichever price pharma sets, it’s that.

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10 points

Sounds crazy they are but allowed to negotiate?

Is that the same for anything else the government buys? I can’t imagine the army buying 100 tanks and just paying the first price they get?

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5 points

… forbidden by law to negotiate.

Is that true? Is there a legitimate reason why they shouldn’t be able to?

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7 points

United States countries:

I guess I’ll die then

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