Not too long ago, regulations on CBD changed in Germany leading to a plethora of products containing it. As someone who occasionally needs pain medication, I tried some of the products to avoid regular pain killers (ibu). Especially on days with lighter pain, I wished for an alternative to the sledgehammer meds. But I was left standing in the rain. I didn’t feel any effect. That’s why I would love to hear from your experiments and experience.

11 points

CBD has zero effect on me. However, THC ramps my anxiety up to 1000. Maybe I’m just a freak of nature?

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21 points
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THC will cause anxiety and paranoia if your tolerance is low or you use particularly stimulating cannabis strain. This is where CBD is very useful because it decreases psychedelic effect. You can use either a balanced strain (equal or similar THC / CBD content) or supplement CBD in other form.

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3 points

Okay I’m freshman enough to this topic to ask: how do you know what balance you aim for with regards to pain killing?

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5 points

Start with a 1:1 and adjust from there.

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11 points

Nah, everyone reacts differently to it, the ones that enjoy it are just a lot more vocal about it.

Personally THC has varied effects for me. Some strains make me space the fuck out (even more so than usual), as if I’m just skipping forward through time, no background thoughts, nothing. Just flash and I’m 20 minutes later. Others make me extremely anxious. Some make me spiral into a really bad depressive ‘everyone hates me. I hate me’ state. Some cause me to pass out, and not in the ‘mmm good sleep’ way, just straight up collapse to the ground pass out. I’ve found very few that have positive effects for me.

So you’re definitely not unusual! The THC anxiety is very real

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4 points
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I think the important distinction here is the percentages of THC present with whatever you’re taking.

If you and @danielton are just talking about getting stoned with cannabis, well yeah it’s going to get you high.

If you guys are talking about taking CBD compound supplements with THC present, that’s very different. THC at low percentages have little to no actual psychoactive effects (talking sub 10% which is way higher than any CBD-specific product can legally be sold as). THC only acts as a catalyst in this fashion.

CDB, CBG, CBC, and CBN, which all occur in different stages of degradation of the THC and CBD compound molecules. CBN is one of the last stages of degradation of THC and is associated with the almost-narcoleptic like sleep and is generally responsible for times that weed knocks you out, which is what I’m guessing happens for you! Not to be one of those vocal enjoyers, moreso highlighting the science behind why you felt the way you have with various strains. It’s certainly the high doses of THC affecting you, but without any CBD compounds there’s nothing to ease the THC.

It’s similar to how we can take an NSAID and an analgesic. Of course we can just have one or the other to get the specific effect, but taking them combined delivers a wider range of effects that go beyond what they were originally meant for. edit The difference is that we have an endocannabinoid system that’s meant to be active and using these theoretically helping prevent the issues in the first place - whereas NSAID and analgesics something we take as a suppressive.

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2 points

Good to know. I tried three different types of it three different times, and one hit and my anxiety was ramped up to 1000. I hated every minute of it.

People I know all tell me marijuana is this universal Good Thing™ that mellows everybody out so I definitely felt like a freak of nature.

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14 points
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CBD’s apparently not really effective for general pain relief, but there’s some data that suggest that it’s effective for neuropathic pain.

I take a full spectrum extract specifically for neuropathic pain and it’s been moderately helpful, and since it’s also immunomodulatory it seems to help some with flare-ups of my autoimmune disease. Not a miracle cure or anything, but it’s been better than nothing and definitely doesn’t make me feel as terrible as the more, uh, pharmaceutical options for treating neuropathic pain such as gabapentin, so I’ve stuck with it.

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3 points
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After consulting my favorite search engine for what neuropathic pain is (not your fault, but language barrier of a non-native speaker) I guess this is what I’m looking for! How do you obtain your CBD? Pharmacy or online?

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3 points
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Online store. It’s Finnish and CBD’s not strictly speaking legal here, but it’s not exactly illegal either and authorities have outright said they don’t know wtf they should be doing with this stuff – so they have the label “small batch collectible product, not for consumption” on their products to cover their asses 😄

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2 points

Is it funny or sad that a finish collectible affects you positively health-wise? Sounds weird but hey. Sometimes laws are lagging behind so much it’s annoying…

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11 points

My wife has chronic neuropathic pain, and the CBD gummies seem to help her sleep. They don’t seem to overtly reduce the pain, but maybe make her less anxious about it.

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4 points

Thank you! I think, this is an aspect I tend to underestimate: the anxiousness pain causes. It is not affecting me much of what I experience, but deep down, it is a thing.

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3 points

Pain is a really interesting thing, and there’s an undeniably subjective aspect of it. My wife has had a chronic pain condition since 2008, and one thing I’ve noticed it’s that her pain is worse when she’s stressed, PMSing, or whatever. There’s no objective way to measure pain, and I think at least part of what’s happening is that her ability to deal with one level of pain gets better or worse depending on her mental state.

I think of it like going out and finding you have a flat tire. If there’s not much going on, you’re not rushed, you had a good night’s sleep, etc., you might just think “Well, that’s annoying,” and deal with it. If you’re sleep deprived, your kid is sick, and you’re under a bunch of pressure at work, you might just want to sit on the curb and cry. Same situation, but your ability to deal with it is different.

Pain is like that, I think. If you’re in a bad place, things seem to hurt more because your ability to deal with the pain is less.

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Only with CBD products bought at a marijuana dispensary. The crap they have at gas stations and the like does absolutely nothing.

My favorite has been Mary Jane’s subliminal tincture. It’s CBD oil in a 1:16 ratio of THC and unlike the other subliminals I’ve tried, they put some flavor in it so it’s like butterscotch and not gross fish oil like flavor that gives me heartburn.

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13 points

There’s been some research and basically those products are unregulated and a good amount of them have zero or negligible actual CBD in them.

Some claim like, grams of CBD and they have zero in them it’s just oil. It’s basically homeopathic CBD.

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2 points

It truly matters who you source it from, biggest lesson someone new needs to learn

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4 points
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the problem is the legality of other cannibinoids where you live …

  • from the states in the US where cannabis has been legalized – neither CBD nor THC will show their full effects in isolation, they each help to augment the other – so even something like a tiny amount of THC added to CBD (ex. 20:1 CBD to THC) will drastically enhance the CBD effects
  • there are two primary (and a lot of secondary) pain systems within the body – one of them responds better to opioids, the other responds better to cannibinoids cannabinoids – everyone’s different and responds differently so it requires a knowledgeable medical professional who hasn’t bought into US’s “reefer madness” propaganda that’s been foisted off onto the rest of the world
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3 points

I’m in bed with a fractured wrist and an opoid intolerance/allergy. Where can I learn more about the dominant pain systems/different solutions you mentioned?

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2 points

proviso: I am not medically trained and most of what I’ve picked up has been informally through the American cannabis communities and legalization efforts

and options for dealing with pain in the US are a hot topic item – you need a medical professional that is knowledgeable about ALL the options but doctors get their licensing at the federal level, not the state level, so they risk their license to even talk about cannabis

from what I’ve stumbled across, opioids work better on acute pain (ex. fractures) and cannabinoids work better on chronic pain (ex. fibromyalgia, stress) – ie. cannabis will help with aches and tension, allowing you to get a night’s sleep – but for direct pain from the fracture, you might be stuck with NSAIDs which have their own slew of issues

I know almost nothing about the other pain systems, but Wikipedia generally has some good starting points

  • cannabinoid
    • “Before the 1980s, cannabinoids were speculated to produce their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. These receptors are common in animals. Two known cannabinoid receptors are termed CB1 and CB2, with mounting evidence of more. The human brain has more cannabinoid receptors than any other G protein-coupled receptor (GPCR) type.”
  • endocannabinoid system
    • “The Endocannabinoid System (ECS) regulates many functions of the human body. The ECS plays an important role in multiple aspects of neural functions, including the control of movement and motor coordination, learning and memory, emotion and motivation, addictive-like behavior and pain modulation, among others.”
    • CB1 receptor
    • CB2 receptor
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2 points
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Thank you for your balanced thoughts! Well your first point kinda might be an issue. I guess I haven’t dived deep enough into this topic to answer whether these mixtures are legally available here. Speaking of it: can you (or someone you know 😉) feel any psychedelic effect of the THC with a 20:1 ratio?

I tried to convince trained professionals twice to go the mentioned route with me. Instead, the looked for me as if I asked for a roofie on the house. So that is another issue…

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3 points
  • most people (depending on tolerance) don’t notice much psychoactive effect from THC below ~5mg
  • from Wikipedia, it looks like in Germany you have to get a medical pass to get access to whole cannabis or THC
  • you will get a similar reaction from doctors in the US
    • in the US, doctors are licensed at the federal level, cannabis is legalized at the state level – doctors risk their license even talking about cannabis regardless of its legality in the state they operate in – no trained professional is going to risk their livelihood
    • most of the world is still victim of the US’s “reefer madness” propaganda campaign (thanks to Nixon and his “War on Drugs”) and it still bears the stigma of “the devil’s weed” – so, unless you find someone knowledgeable, you can expect the attitude of “asking for a roofie” to be the standard response
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