The world’s first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030.
The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side effects.
“We want to do something to help those who are suffering from tooth loss or absence,” said lead researcher Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. “While there has been no treatment to date providing a permanent cure, we feel that people’s expectations for tooth growth are high.”
Following this 11-month first stage, the researchers will then trial the drug on patients aged 2-7 who are missing at least four teeth due to congenital tooth deficiency, which is estimated to affect 1% of people. The team is recruiting for this Phase IIa trial now.
Adult teething products are going to the moon!
Insurance will probably call this cosmetic and not cover it.
God damn - every single post about something good is just filled with sad sacks that have to find something negative to focus on.
Nice of you to just disregard the real suffering that a shitty healthcare and insurance system creates.
Well unfortunately we are all products of our environments, where every single beneficial discovery inevitably becomes a commercial endeavour and priced out of reach of the societies that could benefit most from them. You are entitled to be the cheerleader for the discoverers to your hearts content, just as we are allowed to see and react to the after effects of it
Do you disagree with what they actually said though?
Maybe everyone focuses on the negatives because we just did 5 straight years where it seems like if given the choice between two outcomes positive and negative, we’re living in the timeline where the negative thing always happens.
My point is that some bizarre monoculture has developed where people seem to be pathologically unable to accept that something good happened for a change, and to focus on the good thing. Virtually every comment finds some way to find some ultra-pessimistic take. The very best possible take is nearly always something like “wtf took them so long” or “OK, now do X”.
It should be okay - occasionally - to be happy that something good happened. We have the 98% of other posts out there to moan about and focus on the negative stuff.
It was bad on Reddit, but it seems even worse here.
It’s exhausting.
You should expect every post to have a variety of opinions. Some positive, some negative. Not everybody is going to react to posts the same way you do.
The vast majority of replies in this thread, and to nearly every positive post - are sadsackery.
Differing opinions is fine. Raw, pointless pessimism as a monoculture is…not what you’re describing.
Yussss! Finally I will have the ferret teeth I have dreamed of for so long, and the world will be mine for the taking!
Seriously though, since getting my first filling, I have dreamed of being able to regrow teeth! What an age we live in!
A process called rapid recalcification has existed for almost a decade. I don’t understand why it hasn’t made its way into dentistry yet.
Hard to not be a cynic and assume the ADA (American Dental Association) isn’t wholly made up of “the 10th dentist” lobbying against dental progress but…
That is not the only dental care breakthrough that isn’t widely available in the US (they’re all available and priced for the ‘I don’t actually need to worry about price tags’ crowd, who can also just travel elsewhere) but which would promote healthier lives at the cost of less dentist visits. Curious how it happens.
Can’t wait for it to be $700 a dose.
I had my wisdom teeth removed because I failed to take care of them (dumb teenager), but my dentist told me my jaw fit them just fine, so I never had to lose them.
I want them back.
I had the exact same experience.
I wonder how weird it is to have teeth in the empty flesh spots left there now.
I bet it won’t be weird at all, honestly.
Growing pains, obviously, that’d be weird, but once they’re in, you’d get used to them as easily as you got used to having them removed.
At least, I had mine for a number of years before they were removed. It seems surprising, but I’m used to not having them, and I think the inverse will be equally weird.