The world’s first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030.
The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side effects.
“We want to do something to help those who are suffering from tooth loss or absence,” said lead researcher Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. “While there has been no treatment to date providing a permanent cure, we feel that people’s expectations for tooth growth are high.”
Following this 11-month first stage, the researchers will then trial the drug on patients aged 2-7 who are missing at least four teeth due to congenital tooth deficiency, which is estimated to affect 1% of people. The team is recruiting for this Phase IIa trial now.
This sounds like great news!
Between this and the tooth decay “vaccine” (that replaces acid producing bacteria in the mouth with an alcohol producing kind) there’s no reason my kids shouldn’t reach old age without a full set of their teeth.
Aside from that whole, climate-change-driven-collapse-of-social
-order thing.
I better avoid it through. I had four of my otherwise healthy adult teeth removed early on to avoid crowding issues. No idea where they’d fit in my head now if they grew back
So now instead of getting plaque, I’ll just get tipsy on my saliva? And no one told me?
Insurance will probably call this cosmetic and not cover it.
God damn - every single post about something good is just filled with sad sacks that have to find something negative to focus on.
Nice of you to just disregard the real suffering that a shitty healthcare and insurance system creates.
Well unfortunately we are all products of our environments, where every single beneficial discovery inevitably becomes a commercial endeavour and priced out of reach of the societies that could benefit most from them. You are entitled to be the cheerleader for the discoverers to your hearts content, just as we are allowed to see and react to the after effects of it
You should expect every post to have a variety of opinions. Some positive, some negative. Not everybody is going to react to posts the same way you do.
The vast majority of replies in this thread, and to nearly every positive post - are sadsackery.
Differing opinions is fine. Raw, pointless pessimism as a monoculture is…not what you’re describing.
Do you disagree with what they actually said though?
Maybe everyone focuses on the negatives because we just did 5 straight years where it seems like if given the choice between two outcomes positive and negative, we’re living in the timeline where the negative thing always happens.
My point is that some bizarre monoculture has developed where people seem to be pathologically unable to accept that something good happened for a change, and to focus on the good thing. Virtually every comment finds some way to find some ultra-pessimistic take. The very best possible take is nearly always something like “wtf took them so long” or “OK, now do X”.
It should be okay - occasionally - to be happy that something good happened. We have the 98% of other posts out there to moan about and focus on the negative stuff.
It was bad on Reddit, but it seems even worse here.
It’s exhausting.
There’s already several comments about how expensive it would be in the US along with dental care in general, but IIRC a lot of other countries leave dentistry out of their health care plans as well. Any country that can foresee this as becoming freely available want to speak up?
In Finland dental care
• is free for students (~70€/year for upper education)
• is free if you are unable to work and have no income
• has payment ceiling of 762€/year for everyone else (other healthcare is included in this also)
Medicine also has payment ceiling of 627€/year after which you pay 2.50€ for any medicine
So not completely free but pretty manageable I would say
How does Finland handle naturalization? I’m not well off by any measure but I’m more than happy to jump through every hoop to get out of my shit hole nation.
I’m not familiar with it but you should find all the info here
Can’t wait for it to be $700 a dose.
