34 points

For anyone considering regular recreational benadryl use, please read this link:

https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667

This study examines OTC anticholinergics use in a group of 3500 people 65 and older in Seattle, Washington at two points in time, an average of 7 years apart.

In that time, 800 individuals developed dementia and they found that anticholinergic use resulted in an increased risk of dementia. There is a dose-dependent relationship as well, the higher the cumulative dose meant a greater risk of developing dementia.

From the article:

“Taking an anticholinergic for the equivalent of three years or more was associated with a 54% higher dementia risk than taking the same dose for three months or less.”

Granted, this study is looking at persons 65 and older, which do have an altered drug metabolism compared to younger persons, but even so it’s not looking good generally for humans to have chronic exposure to drugs like Benadryl.

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13 points

Brb strapping in for the wildest 2 years, 11 months of my life.

Thanks for posting this though. Remember folks, even the super safe drugs are only safe for their intended purpose and dose.

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31 points

This is why I always stop at 425 for regular use, just to be on the safe side

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21 points

The what?!

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44 points

Diphenhydramine, sold as Benedryl, can cause hallucinations when overdosing. Some people purposefully overdose on Benedryl to hallucinate. “The Hatman” refers to seeing something that looks like a shadowy figure of a person wearing a hat.

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12 points

Oh i see. Didn’t realize that was used recreationally.

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18 points

FYI: I’ve tried it and it’s not worth it. It’s a very paranoid and anxious high.

I’ve also been told it’s pretty dangerous to use long term, but I don’t remember any of the facts

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16 points

I never hear good things about it. Mostly hallucinations about spiders and bugs in the corners and other very unsettling things. It’s basically sleep paralysis

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11 points

Do not fuck with benadryl.

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4 points

Kids called it “triple C’s” where I was from

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4 points

Aka a deliriant substance.

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2 points

eesti?

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